HIV-1 subtypes in Yugoslavia.

نویسندگان

  • Maja Stanojevic
  • Anna Papa
  • Evagelia Papadimitriou
  • Sonja Zerjav
  • Djordje Jevtovic
  • Dubravka Salemovic
  • Tanja Jovanovic
  • Antonis Antoniadis
چکیده

To gain insight concerning the genetic diversity of HIV-1 viruses associated with the HIV-1 epidemic in Yugoslavia, 45 specimens from HIV-1-infected individuals were classified into subtypes by sequence-based phylogenetic analysis of the polymerase (pol) region of the viral genome. Forty-one of 45 specimens (91.2%) were identified as pol subtype B, 2 of 45 as subtype C (4.4%), 1 of 45 as CRF01_AE (2.2%), and 1 as CRF02_AG recombinant (2.2%). Nucleotide divergence among subtype B sequences was 4.8%. Results of this study show that among HIV-1-infected patients in Yugoslavia subtype B predominates (91.5%), whereas non-B subtypes are present at a low percentage, mostly related to travel abroad.

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عنوان ژورنال:
  • AIDS research and human retroviruses

دوره 18 7  شماره 

صفحات  -

تاریخ انتشار 2002